“Nano Comes to Life”: DNA NanoTech, Medicine and the Future of Biology with Professor Sonia Contera

Nano Comes to Like on Bridging the Gaps

Nanotechnology allows scientists to better understand, interact with, and manipulate biology by creating and manufacturing artificial structures and even machines at the nanoscale out of DNA, proteins, and other biological molecules. From nanoscale machines that can target individual cancer cells and deliver drugs more effectively to nanoantibiotics that can fight resistant bacteria, to the engineering of tissues and organs for research, drug discovery, and transplantation, nanotechnology is revolutionizing medicine in ways that will have profound effects on our health and longevity.

In this episode of Bridging the Gaps I speak with Professor Sonia Contera and we discuss fascinating research that she presents in her book “Nano Comes to Life: How Nanotechnology Is Transforming Medicine and the Future of Biology”. The book introduces readers to nanotechnologies, which are fast advancing and allowing us to influence the basic building components of life. Sonia Contera provides an insider’s view of this new frontier, explaining how nanotechnology permits a new sort of transdisciplinary science that has the potential to give us power over our own biology, health, and lifestyles. Sonia Contera is professor of biological physics in the Department of Physics at the University of Oxford. Her work lies at the interface of physics, biology, and nanotechnology, with a particular focus on the role of mechanics in biology.

We start by discussing the scale at which nanotechnologies function. The evolution of instruments and technology that allow us to perceive and interact with matter on such a microscopic scale is then discussed. The convergence of numerous sciences that are at the heart of such breakthroughs are then discussed, allowing us to build nano-scale structures from the ground up. We then discuss the fascinating research that enables researchers to design proteins on a computer simulator, figure out what kind of GENOME will make such protein from that simulated protein, create that GENOME, and then put it in a real cell to create that protein in reality. We also touch upon the cutting edge research in DNA Nanotechnology and other enabling technologies such as Artificial Intelligence, and the future of biology and medicine. This has been a fascinating discussion.

Complement this discussion by listening to “Artificial Intelligence: Fascinating Opportunities and Emerging Challenges with Professor Bart Selman and then listen to Is Philosophy Dead? On the Bittersweet Relationship Between Science and Philosophy” with Professor Tim Maudlin.

By |August 22nd, 2021|Artificial Intelligence, Biology, Nano Technology, Physics, Research, Technology|
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“Free Will” Through the Lenses of Philosophy and Neuroscience with Dr Alfred Mele

"Surrounding Free Will"

The debate over whether or not free will exists is not new. The main points of contention in this discussion are whether or not we have control over our actions, and if so, what kind of control we have and to what extent. On the one hand, we have a strong sense of liberty, which causes us to trust in our own free will. An intuitive and instinctive sense of free will, on the other hand, could be misinterpreted. In this episode of Bridging the Gaps, I speak with Dr Aflred Mele and we discuss the concept of “Free Will” from the perspective of philosophy and from the perspective of neuroscience.

Dr Alfred Mele is a Professor of Philosophy at Florida State University. His research interests include issues about human behavior located at the intersection of philosophy and science such as free will, personal autonomy, self-deception, self-control, intention, intentional action, motivation, and moral responsibility. He is also the past Director of the Philosophy and Science of Self-Control Project and the Big Questions in Free Will Project.

I open this discussion by asking Dr Mele to unpack the concept of “Free Will”. I then ask Dr Mele to outline important philosophical views about the concept of “Free Will” that emerged over time. We discuss in detail the relevant concepts of determinism, compatibilism, incompatibilism, and libertarianism. We then discuss the concept of Free Will through the lens of neuroscience. We discuss a number of experiments conducted by neuroscientists. The finding of these experiments seems to suggest that that free will is an illusion. But the question is, is it right to extrapolate the findings of these experiments that focus on simple choices and are conducted in controlled environments to conclusively suggest that free will does not exist. Dr Mele discusses this point in detail.

Complement this conversion with fascinating discussion with Professor Renata Salecl on “A Passion of Ignorance and Denials” and then listen to Professor David Chalmers in: “From Consciousness to Synthetic Consciousness”.

By |July 25th, 2021|Neuroscience, Philosophy, Podcasts, Research|
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Time, Space and Nature of Reality through the Lens of Quantum Theory with Dr Carlo Rovelli

What is time? Is time real or just an illusion? Time is an enigma, a mystery that never ceases to perplex us. Philosophers, poets, painters and thinkers have long debated its significance, while scientists have discovered that its structure differs from our intuitive understanding of it. Our view of time has changed dramatically throughout the years, from Boltzmann to quantum theory, and from Einstein to loop quantum gravity. In the huge cosmos, time moves at various speeds in different places, the past and future differ considerably less than we might assume, and the whole concept of the present vanishes. In this episode of Bridging the Gaps I discuss with Dr Carlo Rovelli the nature of time, the nature of space, and the fundamental nature of reality through the lens of quantum mechanics.

Carlo Rovelli is professor of physics at Aix-Marseille University, where he is director of the quantum gravity group at the Center for Theoretical Physics. He is one of the founders of loop quantum gravity theory and is one of the world’s biggest experts in this field.

In his books and in his presentations Rovelli says time is not what we think it is. He also says that space is not what we think it is. I open our conversation by asking him to unpack these statements for us. We then discuss the “impossibility of now”. In physics, from one moment to the next, the only concept that gives some notion of continuity is the flow of heat; it is the concept of entropy. We discuss how entropy plays an important role in this perceived continuity. Along the way we touch upon the concepts of past, present and future that we hold in our minds. Dr Rovelli’s new book, Helgoland begins with a detailed description of the development of quantum theory in 1925; we discuss the main observations and discoveries that led to the development of quantum theory. We then discuss the fundamental nature of reality by unpacking the statement in one of his books “if the backdrop of space has disappeared, time has disappeared, classic particles have disappeared, along with the class fields, so then what is the world made of?” And finally we discuss the efforts to develop models and theories to reconcile general relativity with quantum theory. We discuss how loop quantum gravity theory attempts to reconcile general relativity with quantum theory.

Complement this conversion with fascinating discussion with Dr Katie Mack on “The End of Everything” and then list to at: Dr Dan Hooper on “Our Universe’s First Few Seconds”

By |June 13th, 2021|Cosmology, Physics, Podcasts|
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