“The Network of Life: A New View of Evolution” with Professor David Mindell

The Network of Life: A New View of Evolution on Bridging the Gaps

For a long time, the prevailing perspective on evolution has been that it follows a vertical pathway, where genetic information is passed down from one generation to the next in a linear fashion, resembling a “tree of life.” This classical view suggests that species evolve through a process of divergence from common ancestors, resulting in a branching tree structure that traces the lineage of life over time. In his new book “The Network of Life” Professor David Mindell emphasises the need to update this understanding, and explains that evolution functions more like a distributed, decentralised network. In this framework, there are possibilities for horizontal evolution, where genetic material is shared across species in a more fluid and interconnected manner. The book looks at the forces behind horizontal evolution, such as interbreeding, genetic recombination, merging of species, horizontal gene transfer, and coevolution. The network view of evolution leads to a new symbiotic theory of health. It suggests that the future well-being of humans, other species, and our environment relies on how life evolves and adapts within this interconnected web. In this episode of Bridging the Gaps I speak with Professor David Mindell.

Professor David Mindel is a senior researcher of Zoology at the University of California, Berkeley. He is a former professor of ecology and evolutionary biology at the University of Michigan, director of the University of Michigan Museum of Zoology, and Dean of Science at the California Academy of Sciences.

We begin our discussion by revisiting the traditional concept of vertical evolution, where life is represented as a branching tree. This model shows how species evolve through a series of splits, tracing their lineage back to common ancestors. We explore how this classical framework explains the development of species over time and then shift to discussing two core ideas in evolutionary theory: natural selection and genetic mutation. For much of history, evolution has been viewed primarily through the lens of vertical inheritance, which emphasises the transmission of traits from parent to offspring.

One reason for this focus on vertical evolution is that early evolutionary studies, including Darwin’s, were centred around natural selection, with limited knowledge about genetic mutations. At that time, the role of genetic mutations was not well understood. Today, we know they are essential drivers of evolution. We examine how this early gap in understanding may have shaped the preference for the vertical model of evolution and consider whether it limited perspectives on how species adapt over time.

Next, we delve into the concept of horizontal evolution, which presents a shift from the traditional view. In “The Network of Life”, Professor David Mindell explores evidence suggesting that horizontal evolution—where genes are shared across species—has been happening since life began on Earth. To set the stage, I ask him to outline what we currently know about the origins of life. We also discuss the intriguing role of viruses, which can transfer genetic material between species and influence evolutionary paths.

We then dive into the key discoveries that support and solidify the concept of horizontal evolution. Processes such as hybridization, species merging, and horizontal gene transfer provide strong evidence for this interconnected view of life. Mindell highlights the contributions of prominent scientists and pivotal studies that have reshaped our understanding of evolution.

If we update the current evolutionary framework to include horizontal evolution, what new questions might this approach help us answer? We discuss the significance of adopting this broader perspective and how it could refine our understanding of life’s history.

Finally, we explore the exciting possibilities that arise from this new understanding. By embracing the network view of evolution, we can enhance research on synthetic life, support assisted evolution to help species adapt to climate change, and revolutionise our approaches to biotechnology, medicine, and environmental sustainability. This has been an insightful and enriching conversation, shedding light on the profound impact of horizontal evolution on our world.

Complement this discussion with “Zero to Birth: How the Human Brain Is Built” with Professor William Harris and then listen to “The Exquisite Machine: The New Science of the Heart” with Professor Sian Harding

By |October 19th, 2024|Biology, Future, History, Knowledge, Podcasts, Research|
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“Off-Earth: Ethical Questions and Quandaries for Living in Outer Space” with Dr Erika Nesvold

Off Earth book reviewed at Bridging the Gaps: A Portal for Curious Minds

As humanity sets its sights on venturing beyond the confines of Earth, it is immensely important to acknowledge that the journey to space is not merely a technological feat, but a profoundly human endeavour. From pinpointing destinations to preparing flight plans, from developing generational ships to designing habitats, from selecting teams to establishing communities, there is a crucial element that must not be overlooked: the human dimension. From fostering a sense of community and shared purpose among spacefarers to grappling with the enforcement of laws and the establishment of governance structures in extraterrestrial settlements, addressing these aspects is essential for the success and sustainability of our off-world endeavours. Erika Nesvold’s insightful book “Off-Earth: Ethical Questions and Quandaries for Living in Outer Space” serves as a timely reminder that space exploration isn’t solely about the scientific and technical aspects—it’s about grappling with the very human dilemmas that accompany such endeavours. In the episode of Bridging the Gaps, I speak with Dr Erika Nesvold.

Dr Erika Nesvold is an astrophysicist who has worked as a researcher at NASA Goddard and the Carnegie Institution for Science. She is a developer for Universe Sandbox, a physics-based space simulator. She is a co-founder of the nonprofit organisation the JustSpace Alliance. Erika is the creator and host of the podcast Making New Worlds.

We began by discussing the significance of understanding the human aspect of space exploration. The book covers a wide variety of topics and in our discussion we touch upon ethical, social and legal complexities that must be understood and adopted or redeveloped for our extraterrestrial settlements. We also discuss the concepts and principles that can be borrowed from the laws and charters devised during humanity’s exploration of open seas and oceans. Central to our discussion is the importance of initiating a dialogue now to foster an understanding of how our humanity intersects with the challenges and opportunities presented by space exploration. This understanding, we discuss, is fundamental in shaping a future that upholds ethical principles and fosters social equity.

Complement this discussion with “A Traveller’s Guide to the Stars” with Physicist, Author and Nasa Technologist Les Johnson and then listen to “The Next 500 Years: Engineering Life to Reach New Worlds” with Professor Christopher Mason.

By |April 28th, 2024|Future, Podcasts, Research|
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“Sharing Our Science: How to Write and Speak STEM” with Professor Brandon Brown

Sharing Our Science book reviewed on Bridging the Gaps

Science communication plays an important role in bridging the gap between researchers and the general public, fostering understanding, engagement, and appreciation for scientific explorations and advancements. In an era where science and technology shape every aspect of our lives, effective communication of research findings is more critical than ever. This is also a time where there are conflicting views about scientific work and polarizations in societies. This makes effective science communication even more important not only to ensure that scientific knowledge is accessible to all, but also to empower individuals to make informed decisions, influences policy-making, and fosters trust in the scientific community. However, effective science communication goes beyond simply disseminating information; it requires clarity, creativity, and engagement strategies tailored to diverse audiences. By employing clear language and compelling storytelling researchers can effectively communicate their findings, thereby enhancing public awareness and understanding of the profound impact that science has on society. In his recent book “Sharing Our Science: How to Write and Speak STEM” Professor Brandon Brown, a scientist-turned-writing teacher, provides a highly valuable resource for STEM practitioners aiming to effectively convey their technical work to both specialised and general audiences. In this episode of Bridging the Gaps I speak with Professor Brandon Brown; we discuss this personal, practical, and inspirational guide for scientists and technical professionals seeking to enhance their written and oral communication skills in STEM fields.

Brandon Brown is a Professor of Physics and communications specialist at the University of San Francisco. He is an excellent science communicator. He has written for publications such as Slate, Smithsonian, and Scientific American and served as Deputy Director at the Green Science Policy Institute and a Senior Writing Coach for the Strictly Speaking Group.

We begin by exploring the significance of storytelling in effective science communication, delving into diverse tools and approaches such as tension and narrative to enhance the communication of scientific concepts. We further examine the utilisation of relatable examples, including simplifying large numbers and intricate comparisons like the size of an atom relative to its nucleus, to improve clarity and facilitate comprehension. We also address the detrimental effects of disinformation on science communication, which can lead to societal polarisation and divisions. We also reflect on Professor Brandon Brown’s personal encounters, highlighting how adept communication of challenging facts can profoundly influence individuals. This has been both informative and insightful discussion.

Complement this discussion with On Public Communication of Science and Technology with Professor Bruce Lewenstein and then listen to “The Joy of Science” with Professor Jim Al-Khalili

By |February 7th, 2024|Information, Knowledge, Podcasts, Research|
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