“From Sensing to Sentience: How Feeling Emerges from the Brain” with Professor Todd Feinberg

From Sensing to Sentience on Bridging the Gaps

Sentience is the feeling aspect of consciousness, encompassing the capacity to experience sensations such as pain, pleasure, and emotions. It is the foundation of subjective experience, distinguishing beings that can feel from those that merely process information or react reflexively. Sentience is a crucial component of consciousness. A key question in studying sentience is how it emerges—whether it arises from complex neural processes, a particular form of computation, or something more fundamental. In his book “From Sensing to Sentience: How Feeling Emerges from the Brain”, Professor Todd Feinberg introduces “Neurobiological Emergentism (NBE)”, a theory explaining how sentience naturally arises as an emergent property of brain functions. Emergent properties are features of a system that do not exist in its individual parts but arise through their interactions. Integrating biological, neurobiological, evolutionary, and philosophical perspectives, Feinberg argues that sentience emerges as a “system-level property” of complex neural interactions. In this episode of Bridging the Gaps, I speak with Professor Todd Feinbergy.

Dr. Todd Feinberg is a board certified neurologist and psychiatrist and Clinical Professor of Psychiatry at the Icahn School Medicine at Mount Sinai in New York City.

We begin by exploring the basic sensory abilities of single-celled organisms, examining how they react to their environment and survive. We then trace the evolution of multicellular organisms, discussing that when they developed into more complex systems, there is a broader substrate for sensing. A key focus is how sensory abilities laid the foundation for the evolution of advanced neurobiological systems, ultimately leading to sentience. We discuss in detail how simple sensory functions in early life forms gradually evolved into the rich experiences of animals with complex nervous systems.

A central idea in the book is that “sentience emerges” as a property of complex neural systems. This perspective helps bridge the gap between neuroscience and philosophy, providing a natural explanation for how subjective experiences arise from the brain. We explore this argument in depth. Overall, this discussion provides valuable insights into the origins of sentience and its role in the evolution of consciousness.

Complement this discussion with “Sentience: The Invention of Consciousness” with Professor Nicholas Humphrey and then listen to “The Network of Life: A New View of Evolution” with Professor David Mindell

By |February 9th, 2025|Neuroscience, Podcasts, Research|

“The Evolution of Biological Information: How Evolution Creates Complexity, from Viruses to Brains” with Professor Christoph Adami

Evolution of Biological Information on Bridging the Gaps

Consider this thought-provoking statement: “Life is information that maintains itself.” This argument, proposed by Professor Christoph Adami in his book “The Evolution of Biological Information: How Evolution Creates Complexity, from Viruses to Brains” places information at the heart of biological systems. Adami’s innovative perspective offers fresh insights into phenomena such as the evolution of drug resistance in viruses, the development of cellular communication, and the emergence of intelligence. By framing information as the unifying principle of biology, this approach provides a systematic way to explore the origin of life—both on Earth and beyond. In this episode of Bridging the Gaps I speak with Professor Christoph Adami.

Christoph Adami is professor of microbiology and molecular genetics & physics as well as astronomy at Michigan State University. A pioneer in the application of methods from information theory to the study of evolution, he designed the Avida system that launched the use of digital life as a tool for investigating basic questions in evolutionary biology. He has received several awards, including the NASA Exceptional Achievement Medal and the Lifetime Achievement Award from the International Society for Artificial Life.

We begin with an in-depth exploration of Shannon’s information theory, focusing particularly on the concept of entropy. This foundation sets the stage for a discussion on how biological systems store and preserve information. We delve into the information content of genes and proteins, highlighting a key idea from the book: “Living organisms know some very important facts about the world they inhabit and thrive in.”

Next, we examine the concept of genetic information and its storage within DNA molecules and genomes. This includes a detailed look at the nature of this information and the latest understanding of the data encoded within the genome.

We then turn to the core mechanisms—or laws—of evolution: inheritance, variation, and selection, framing these processes as the measurement, processing, and transmission of information. To describe evolution through the lens of information theory, Adami incorporates the concept of Maxwell’s demon, a thought experiment that challenges the second law of thermodynamics. We discuss this thought experiment in detail and its application to understanding the evolution of biological information.

Finally, we explore the profound question of the origin of life, accompanied by an engaging discussion on viruses. Before finishing this discussion, we also touch upon the nature and challenges of multidisciplinary research. Overall, this has been an enlightening and highly informative journey into the intersection of biology and information theory.

Complement this discussion with “The Network of Life: A New View of Evolution” with Professor David Mindell and then listen to “Zero to Birth: How the Human Brain Is Built” with Professor William Harris

By |December 21st, 2024|Biology, Information, Podcasts, Research|

“The Painful Truth about Hunger in America” with Professor Mariana Chilton

Hunger is far more than the immediate and tangible experience of not being able to find or buy food. While it is true that hunger is often depicted as the physical sensation of an empty stomach—a condition that can be temporarily alleviated by food—the issue runs much deeper. Hunger is more than the absence of food; it is a manifestation of deeper, societal and structural failings leading to individual and collective trauma. To genuinely combat hunger, we must engage with its underlying causes—economic inequality, systemic discrimination, and societal neglect—and strive to create a compassionate and just society where all people have the resources, respect, and opportunities they need to thrive. In her book “The Painful Truth about Hunger in America: Why We Must Unlearn Everything We Think We Know—and Start Again” professor Mariana Chilton presents a bold, transformative perspective on addressing hunger and poverty in the United States. The book emphasises that hunger in the United States is underpinned by profound societal and structural failures that perpetuate poverty and ensure that millions remain trapped in cycles of scarcity. In this episode of Bridging the Gaps I speak with professor Mariana Chilton.

Although the book focuses on the issues of hunger and poverty in the United States, the human experiences and the underlying structural and social root causes it explores are often universal. The insights and key points raised in the book resonate with similar challenges faced in other societies and regions, making its research and findings valuable for broader learning and application.

Mariana Chilton is a Professor of Health Management and Policy at Drexel University’s Dornsife School of Public Health. She is the founder of the Center for Hunger-Free Communities, where she initiated impactful programs such as “Witnesses to Hunger”, aimed at amplifying women’s voices in the national conversation on hunger and poverty, and the “Building Wealth and Health Network”, which focuses on fostering economic security and healing. Chilton has provided expert testimony on hunger solutions before both the US Senate and the House of Representatives.

Our discussion delves into the intricate connections between hunger and trauma, revealing the emotional and psychological toll on individuals and communities. We examine the persistent nature of poverty and its link to generational trauma and explore the complex relationship between poverty, violence, and systemic inequalities. Professor Chilton provides thoughtful explanations supported by real-world examples and personal stories, many of which are detailed in her book. We also discuss challenges involved in conducting research on such sensitive topics, particularly when working with vulnerable populations. The discussion covers both ethical considerations and the logistical obstacles researchers face when collecting data and sharing findings in a manner that respects and empowers participants. Professor Chilton’s insights shed light on the importance of compassionate, inclusive approaches to research and advocacy that prioritise the voices of those most affected by these issues.

Complement this discussion with “The Blind Spot: Why Science Cannot Ignore Human Experience” with Professor Adam Frank and then listen to “A Passion for Ignorance” and for Denials and Negations with Professor Renata Salecl.

By |November 17th, 2024|Podcasts, Research, Social Science, Sustainability|