“Nano Comes to Life”: DNA NanoTech, Medicine and the Future of Biology with Professor Sonia Contera

Nano Comes to Like on Bridging the Gaps

Nanotechnology allows scientists to better understand, interact with, and manipulate biology by creating and manufacturing artificial structures and even machines at the nanoscale out of DNA, proteins, and other biological molecules. From nanoscale machines that can target individual cancer cells and deliver drugs more effectively to nanoantibiotics that can fight resistant bacteria, to the engineering of tissues and organs for research, drug discovery, and transplantation, nanotechnology is revolutionizing medicine in ways that will have profound effects on our health and longevity.

In this episode of Bridging the Gaps I speak with Professor Sonia Contera and we discuss fascinating research that she presents in her book “Nano Comes to Life: How Nanotechnology Is Transforming Medicine and the Future of Biology”. The book introduces readers to nanotechnologies, which are fast advancing and allowing us to influence the basic building components of life. Sonia Contera provides an insider’s view of this new frontier, explaining how nanotechnology permits a new sort of transdisciplinary science that has the potential to give us power over our own biology, health, and lifestyles. Sonia Contera is professor of biological physics in the Department of Physics at the University of Oxford. Her work lies at the interface of physics, biology, and nanotechnology, with a particular focus on the role of mechanics in biology.

We start by discussing the scale at which nanotechnologies function. The evolution of instruments and technology that allow us to perceive and interact with matter on such a microscopic scale is then discussed. The convergence of numerous sciences that are at the heart of such breakthroughs are then discussed, allowing us to build nano-scale structures from the ground up. We then discuss the fascinating research that enables researchers to design proteins on a computer simulator, figure out what kind of GENOME will make such protein from that simulated protein, create that GENOME, and then put it in a real cell to create that protein in reality. We also touch upon the cutting edge research in DNA Nanotechnology and other enabling technologies such as Artificial Intelligence, and the future of biology and medicine. This has been a fascinating discussion.

Complement this discussion by listening to “Artificial Intelligence: Fascinating Opportunities and Emerging Challenges with Professor Bart Selman and then listen to Is Philosophy Dead? On the Bittersweet Relationship Between Science and Philosophy” with Professor Tim Maudlin.

By |August 22nd, 2021|Artificial Intelligence, Biology, Nano Technology, Physics, Research, Technology|
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Time, Space and Nature of Reality through the Lens of Quantum Theory with Dr Carlo Rovelli

What is time? Is time real or just an illusion? Time is an enigma, a mystery that never ceases to perplex us. Philosophers, poets, painters and thinkers have long debated its significance, while scientists have discovered that its structure differs from our intuitive understanding of it. Our view of time has changed dramatically throughout the years, from Boltzmann to quantum theory, and from Einstein to loop quantum gravity. In the huge cosmos, time moves at various speeds in different places, the past and future differ considerably less than we might assume, and the whole concept of the present vanishes. In this episode of Bridging the Gaps I discuss with Dr Carlo Rovelli the nature of time, the nature of space, and the fundamental nature of reality through the lens of quantum mechanics.

Carlo Rovelli is professor of physics at Aix-Marseille University, where he is director of the quantum gravity group at the Center for Theoretical Physics. He is one of the founders of loop quantum gravity theory and is one of the world’s biggest experts in this field.

In his books and in his presentations Rovelli says time is not what we think it is. He also says that space is not what we think it is. I open our conversation by asking him to unpack these statements for us. We then discuss the “impossibility of now”. In physics, from one moment to the next, the only concept that gives some notion of continuity is the flow of heat; it is the concept of entropy. We discuss how entropy plays an important role in this perceived continuity. Along the way we touch upon the concepts of past, present and future that we hold in our minds. Dr Rovelli’s new book, Helgoland begins with a detailed description of the development of quantum theory in 1925; we discuss the main observations and discoveries that led to the development of quantum theory. We then discuss the fundamental nature of reality by unpacking the statement in one of his books “if the backdrop of space has disappeared, time has disappeared, classic particles have disappeared, along with the class fields, so then what is the world made of?” And finally we discuss the efforts to develop models and theories to reconcile general relativity with quantum theory. We discuss how loop quantum gravity theory attempts to reconcile general relativity with quantum theory.

Complement this conversion with fascinating discussion with Dr Katie Mack on “The End of Everything” and then list to at: Dr Dan Hooper on “Our Universe’s First Few Seconds”

By |June 13th, 2021|Cosmology, Physics, Podcasts|
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“Exploring the Mysteries of Our Universe’s First Seconds” with Dr Dan Hooper

Scientists now have a good understanding of how our universe evolved over the past 13.8 billion years, but we know very little about what happened in the first few seconds after the Big Bang. Dr Dan Hooper, a senior scientist at Fermi National Accelerator Lab and a professor of astronomy and astrophysics at the University of Chicago, emphasises that understanding the earliest moments of the universe is vital to tackle, and to decipher mysteries such as dark matter and dark energy. In his book “At the Edge of Time: Exploring the Mysteries of Our Universe’s First Seconds” Hooper outlines four foundational questions as puzzles that we must solve and the key to solving these puzzles is in understanding what happened at the very beginning of our universe.

In this episode of Bridging the Gaps I speak with Dr Dan Hooper. We discuss intriguing questions and fascinating research that he presents in the book “At the Edge of Time: Exploring the Mysteries of Our Universe’s First Seconds”. At the start of the book Hooper gives a thorough description of the timeline of how we got here where we are now from the Big Bang to the present day and how did our universe evolve over the past 13.8 billion years; he presents this narrative backwards, from the present time to the Big Bang. I open our conversation by asking him to describe this timeline and this journey from the present day to the Big Bang. We then discuss the four puzzles that Hooper outlines in the book and examine that understanding what happened in the first few seconds after the Big Bang holds the key to solving these puzzles. We also discuss the progress that is being made in developing a theory of everything, gravitational waves and his views on the multi universe theory. This has been a fascinating discussion with a very passionate researcher.

Compliment Professor Hooper’s insights with equally fascinating discussion with Dr Katie Mack “The End of Everything (Astrophysically Speaking”, and then listen to discussion with Nasa’s Spitzer project scientist Michael Werner “Spitzer Space Telescope: Discovering “More Things in the Heavens”.

By |September 20th, 2020|Cosmology, Physics, Podcasts|
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