“The Next 500 Years: Engineering Life to Reach New Worlds” with Professor Christopher Mason

We are the only known species that understands species go extinct. We also understand that climate calamity, apocalyptic war, or the demise of the sun in a few billion years will all inevitably bring life on Earth to an end. So it is extremely important we do whatever we can to avoid extinction. We have a moral obligation to prevent extinction, and we have a responsibility to act as life-form shepherds—not just for our species, but for all species on which we rely, as well as those yet to come. This may involve finding a new home planet, developing innovative ways to undertake long haul space journeys. This may also involve re-engineering life and human genetics for travelling to, and for surviving on other worlds. Dr Christopher Mason argues in his provocative and engaging book “The Next 500 Years: Engineering Life to Reach New Worlds” that we have a moral duty to do just that. In this episode of Bridging the Gaps I speak with Dr Christopher Mason and we discuss his inspiring vision of the next 500 years of spaceflight and human exploration.

Dr Christopher Mason is a professor of genomics, physiology, and biophysics at Weill Cornell Medicine and the Director of the WorldQuant Initiative for Quantitative Prediction. He is a geneticist and computational biologist who has been a Principal Investigator and Co-investigator of 11 NASA missions and projects.

We start by discussing the moral obligation, moral duty that we must protect our species against extinction and to ensure that life continues. We discuss the impact of living in hard and unfamiliar environment of space on the human body and talk through the findings of “the Twin Study” which examines the impact of nearly a full year in space on astronaut Scott Kelly, using his identical brother Mark as control. We then discuss moral and ethical dimensions of engineering life and making changes in human genome and undertaking genetic modifications of humans. We review the 500 years plan that Dr Chris Mason presents in this book and go through various phases of this plan. We talk about engineering of genomes, cellular engineering, synthetic biology and preparing humans for long haul space flights. We discuss in detail how CRISPR tool works and what it enables us to do. We also discuss feature and functional re-engineering of the human genome by borrowing features and functions from other species. We once again touch upon moral, ethical, and social implications of re-engineering life and try to imagine a future full of variety of life forms evolved through directed and iterative re-engineering of life, coming from the same source that is human.

Complement this discussion with The End of Astronauts”, Robotic Space Exploration and Our Future on Earth and Beyond with Professor Martin Rees and then listen to “Nano Comes to Life”: DNA NanoTech, Medicine and the Future of Biology with Professor Sonia Contera

By |May 19th, 2022|Biology, Future, Physics, Podcasts, Research|
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“The Joy of Science” with Professor Jim Al-Khalili

Can living scientifically empower us to navigate the complexities of today’s complex and unpredictable world? Can the joy of critical thinking and the effectiveness of the scientific method assist us in making better decisions? Can living a more rational life help us navigate modern life more confidently? In his new book “The Joy of Science” acclaimed physicist Jim Al-Khalili invites readers to engage with the world as scientists have been trained to do. He shows how the fundamental principles at the heart of scientific thinking, as well as the scientific process, are profoundly relevant to the perplexing times we live in and the tough choices we make. In this episode of Bridging the Gaps, I speak with professor Jim Al-Khalili and we thoroughly discuss very interesting and deeply intriguing ideas that he presents in this book.

Professor Jim Al-Khalili is a theoretical physicist at the University of Surrey where he holds a Distinguished Chair in physics as well as a university chair in the public engagement in science. He is a prominent author, broadcaster and one of Britain’s best-known science communicators.

I start our discussion with the question that how the discipline of science should be perceived. We acknowledge that there are many ways scientific work is carried out in many different disciplines. We discuss the issue of “relative truth” and how biases held by individuals impact their opinions and distort their view and lead them to their own version of truth. We explore how science deals with the issue of relative truth. We probe how the scientific method enables us to continue researching in the presence of uncertainty. We investigate the impact of misinformation and disinformation on the disciple and cause of science. We also touch upon how rational humans can become; can we think rationally only up to certain point. We discuss in detail how scientific information should be presented to policy makers that should enable and empower them to make better decisions and to make the right choices. Finally, I ask Professor Jim Al-Khalili to tell us about his research in the field of open quantum systems. This has been a fantastic discussion.

Complement this with Asking Better Questions for Creative Problem Solving, Innovation and Effective Leadership with Hal Gregersen and then listen to On Public Communication of Science and Technology with Professor Bruce Lewenstein

By |May 13th, 2022|Biology, Future, Information, Knowledge, Physics, Podcasts, Research, Technology|
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“The End of Astronauts”, Robotic Space Exploration and Our Future on Earth and Beyond with Professor Martin Rees

Human space exploration is challenging as well as fascinating. However, the excitement of space flight for astronauts comes at a high cost and is riddled with danger. As our robot explorers become more capable, governments and corporations must consider whether the ambition to send astronauts to the Moon and Mars is worth the cost and risk. In this episode of Bridging the Gaps, I speak with professor Martin Rees who is one of the authors of “The End of Astronauts: Why Robots Are the Future of Exploration”. The book makes the provocative argument for space exploration without astronauts and suggests that beyond low-Earth orbit, space exploration should proceed without humans. In this discussion, we also touch upon some intriguing points the professor Martin Rees discusses in one of his previous books “On the Future: Prospects for Humanity”.

Martin Rees is an emeritus professor of Cosmology and Astrophysics at the University of Cambridge. He is the UK’s Astronomer Royal, a fellow of Trinity College and a co-founder of the Centre for the Study of Existential Risks at Cambridge University (CSER).

We start by discussing our fascination with human space journeys and exploration. We discuss the title of the book “The End of Astronauts” which seems a bit strong. We then discuss the progress in developing better and smarter robots for robotic space exploration. We discuss the progress made by private space companies in reducing the cost for space missions. Professor Rees emphasise the point that space is hostile and difficult environment and we should avoid using terms as space tourism, instead you should call it space adventures.

We then discuss the book “On the Future: Prospects for Humanity” and touch upon topics such as colonisations of Mars, post human era; genetic engineering and our future on earth and beyond.

Complement this discussion by listening to Everything a Curious Mind Should Know About Planetary Ring Systems with Dr Mark Showalter and then listen to More Things in the Heavens”” with NASA’s Spitzer Project Scientist Michael Werner

By |March 31st, 2022|Cosmology, Future, Physics, Podcasts|
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